Cleaning and decontaminating cleanrooms are critical tasks to ensure both the integrity of the cleanroom itself and the products made within it. The cleaning activities are therefore tightly controlled, with cleaning products, cleaning methods and cleaning frequencies carefully spelled out in detailed standard operating procedures. Not all cleanrooms are cleaned the same way. The specific cleaning products, methods and frequencies are carefully selected based on the cleanroom class, the contaminants of major concern, the products manufactured and the materials of construction within the room itself. As an example, in ISO Class 3 cleanrooms used to manufacture electronic devices minimization of particle levels is critical, while in ISO Class 5 sterile cleanrooms used to manufacture pharmaceutical or biotechnology products minimization of contamination from bacteria and other viables is paramount.
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Following are references that can be consulted for additional information: